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Raj Singh MD
April 21, 2024

Severe Complication of Hormone Pellet Insertion: A Case Report

Severe Complication of Hormone Pellet Insertion

Hormone pellet therapy is a popular treatment option for individuals experiencing hormone imbalances. However, like any medical procedure, there can be complications associated with hormone pellet therapy. Some potential complications of hormone pellet therapy include infection at the insertion site, bleeding or bruising, and extrusion or migration of the pellets.

In this case report we discuss a severe Complication of Hormone Pellet Insertion. These complications can vary in severity and may require medical intervention. In this case report, we described the case of a severe Bleeding after hormone Pellet insertion in a Las Vegas hormone clinic. Patient had initially selected this particular place for pellet insertion due to its low cost of procedure. Patient subsequently transferred his care to our HEALOR™clinic for management of this complication.

Case Report Severe Complication of Hormone Pellet Insertion:

This 74-year-old male presented with low testosterone levels and had been receiving injectable testosterone therapy for a significant period of time. However, he expressed a desire to explore alternative treatment options. In his search for a solution, he came across a hormone clinic in Las Vegas that offered hormone pellets as an alternative treatment option. Intrigued by this option, the patient decided to investigate further.

The procedure of Hormone Pellet Insertion:

The patient had scheduled for a procedure involving the insertion of 6 testosterone pellets, each containing 200 mg. Immediately after the procedure, the patient experienced significant discomfort at the site of the procedure. In order to promote healing and minimize complications, the patient was advised to avoid any physical activity following the procedure.

However, the patient began to experience unusual pain in his right buttock, which radiated all the way down to his leg. Concerned about this sudden change, his wife examined the area and noticed that the whole right leg had turned blue, as can be seen in the picture provided. Worried about her husband's condition, she immediately contacted the clinic for assistance. Unfortunately, the clinic did not address this as a significant complication and advised the patient to continue with routine post-pellet care.

Week 1 post pellet insertion:

The patient in question had been experiencing persistent pain and numbness in the buttock area, as well as throughout their right leg. Despite previous attempts at finding relief, the symptoms continued to worsen. Additionally, the patient began to experience high-grade fevers accompanied by chills, as well as purulent discharge from the site of a previous medical procedure. Concerned about the worsening condition, the patient was referred to an Infectious Disease Doctor for further evaluation.

Upon examination, the Infectious Disease Doctor diagnosed the patient with acute cellulitis and deep fascia infection. To address the infection, a peripherally inserted central catheter (PICC line) was placed, allowing for the administration of intravenous (IV) antibiotics. The patient underwent a six-week course of antibiotic treatment, closely monitored by healthcare professionals.

Following the completion of the antibiotics, the patient experienced complete healing of the infection. Not only did the pain and numbness in the buttock area and right leg subside, but the patient's leg also regained its normal coloration. This successful outcome highlights the importance of prompt diagnosis and appropriate treatment in cases of acute cellulitis and deep fascia infection.


This case serves as a reminder of the possible complications that can arise from a hormone pellet insertion procedure. It is evident that in this particular case, the proper placement of the pellets was not followed, as they were inserted deep into the muscle instead of the intended fat layer. This deviation from the recommended technique can lead to various complications.

One notable complication in this case was the injury to a large blood vessel, which was potentially caused by the trocar used during the procedure. This injury resulted in the development of a hematoma, a collection of blood outside the blood vessels. Such complications can be serious and require immediate attention and intervention. In this case, the clinic dismissed the patient's concerns and did not immediately evaluate the patient for deep vascular injury with an ultrasound.

Furthermore, Using nonsterile methods led to the development of cellulitis, an infection of the skin and soft tissues. In addition, there was also a deep fascia infection observed. These complications highlight the importance of maintaining a sterile environment during the procedure and following proper technique to minimize the risk of infection.

In conclusion, this case emphasizes the potential complications that can occur following a hormone pellet insertion. Adhering to correct anatomical guidelines and ensuring proper technique can help prevent these complications, while maintaining a sterile environment is crucial in reducing the risk of infection.


Hormone pellets have emerged as a safe and effective treatment option for hormone replacement therapy. These small, bioidentical pellets are inserted under the skin and release a steady and consistent dose of hormones into the body. This method of hormone delivery has been found to provide better results compared to other forms of hormone replacement therapy, such as pills or creams. Hormone pellets can be used to treat a variety of conditions, including menopause symptoms, low testosterone levels, and hormonal imbalances.

However, it is crucial to find the right provider for testosterone pellet insertion or hormone pellet insertion. This is because the expertise and experience of the provider can greatly impact the success and safety of the procedure. It is important to choose a provider who is knowledgeable about hormone replacement therapy and has a good track record in performing pellet insertions. They should also have a thorough understanding of your specific hormonal needs and be able to tailor the treatment accordingly.

If you are looking for hormone pellet experts in Las Vegas, HEALOR™ is the place to go. Our team of experienced professionals specializes in hormone replacement therapy and has extensive knowledge in hormone pellet insertion. We understand the importance of personalized care and work closely with each patient to develop a treatment plan that meets their unique needs. Schedule your next hormone pellet insertion with us and experience the benefits of this safe and effective treatment option.

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